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← Return to AIs after hysterectomy?
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Breast Cancer | Last Active: 3 hours ago | Replies (11)
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After menopause estrogen doesn’t come from ovaries but mostly by fat cells that produce aromatase to convert progesterone to estrogen. That’s why old women like us are likely prescribed aromatase inhibitors. The reason we need to have bilateral salpingo oophorectomy surgery is that carriers of pathological BRCA2 mutation have an increased risk of developing ovarian cancer. It’s not to reduce estrogen. If your surgery is prophylactic, ie. you don’t have cancer and the surgery is to prevent cancer, you might not need AIs.
If I’m wrong, please correct me.
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@myoga, seconding this. I had my ovaries/tubes removed after an ATM diagnosis (cervix, uterus was left because if something goes wrong there, it's easier to notice). I asked a few times about any hormonal effect I might notice and my gyn-oncologist reassured me that my post-menopausal little almonds were not doing anything of use. 🙂 And it's true, I've noticed nothing. She also said that if she could, she'd encourage all post-menopausal women to do the same to avoid ovarian cancer. I count one less thing to worry about as a definite up-side to having genetic testing!