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Beginning the Zepbound journey

Bariatric Surgery & Weight Loss | Last Active: 3 hours ago | Replies (69)

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Profile picture for marsha2026 @marsha2026

I’m a 78 year old female just starting Zepbound 2.5 mg. I had a vertical sleeve gastrectomy 11 years ago with moderate weight gain. I’m good at using protein first, drinking water and exercising. But I’m anxious about what to expect the first week or two. What more can I do? What have you experienced?

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Replies to "I’m a 78 year old female just starting Zepbound 2.5 mg. I had a vertical sleeve..."

@marsha2026 - welcome to Mayo Clinic Connect.

Here are a couple of Mayo Clinic articles on
tirzepatide (Zepbound) that may be useful for you:

- Tirzepatide (subcutaneous route) https://www.mayoclinic.org/drugs-supplements/tirzepatide-subcutaneous-route/description/drg-20534045

- Prescription weight-loss drugs
Study the pros and cons of medicines to treat obesity. https://www.mayoclinic.org/healthy-lifestyle/weight-loss/in-depth/weight-loss-drugs/art-20044832

Sounds like you have some good habits already in place. I have taken tirzepatide (Zepbound) previously till I got to the highest dose and my insurance stopped coverage due to a maximum. I honestly don't think much at all happened the week or two I was starting and on the lowest dose. Perhaps others have had different experiences.

If you have to wait awhile to see effects of the tirzepatide (Zepbound), how would you feel about that?