← Return to Lessening P1NP (Bone Formation Marker)on Evenity. What to do?
DiscussionLessening P1NP (Bone Formation Marker)on Evenity. What to do?
Osteoporosis & Bone Health | Last Active: 3 days ago | Replies (10)Comment receiving replies
Replies to "I would really appreciate that, mayblin. Thank you very much!"
@gigilapoisson
Did your doctor try titration (reduced initial dose) until you acclimated to Tymlos ?
Connect

@gigilapoisson
https://pubmed.ncbi.nlm.nih.gov/34020048/
This paper is behind a paywall, but the abstract provides the key information.
The attached figure shows the trajectory of bone turnover markers (BTMs) during the 12mo of Evenity treatment (darker solid line). In the graph, months 13–24 represent the follow-up phase with denosumab (Prolia) vs. placebo.
How long were you on Tymlos?