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Profile picture for mjp0512 @mjp0512

Welcome and so sorry you had to find your way here. If you could post more details from your biopsy, more information will be forthcoming from the group. That said, if your biopsy says Gleason 10, it indicates a pretty aggressive cancer. (I was (am) a Gleason 9 (5+4) with 12 of 12 cores involved so aggressive is in my vocabulary). Next step in the process is a PSMA PET scan to determine if there is any spread outside the prostate capsule. Your Dr will probably also want some germline testing of the tumor. (They'll use material from the biopsy for that.) Treatment options cannot be compiled until after the PSMA PET scan. I will tell you that in my case, I was on ADT (Orgovyx) as soon as the scan was completed. Here's a few things to occupy your time while waiting for the next step. Best wishes!
https://cdn.prod-carehubs.net/n1/748e8fe697af5de8/uploads/2025/03/Prostate-cancer-abbreviations-terms.pdf
https://www.youtube.com/@ThePCRI/videos

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Replies to "Welcome and so sorry you had to find your way here. If you could post more..."

@mjp0512 Great advice, mjp0512.

One clarification for countryhill when he talks with his doctor: testing of the tumor sample from biopsy is "genomic" or "somatic" testing. This is what tests like Decipher and Prolaris do.

"Germline" testing refers to conventional genetic testing for hereditary mutations done through a blood draw: your DNA, not the cancer's.

Both types of testing can be valuable and provide information that could guide treatment decisions.