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Biopsy Number 5: What is going on?

Prostate Cancer | Last Active: Aug 2 5:40pm | Replies (13)

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Just looked at my post and realized the formatting of my PSA history got messed up. Fixed it.

03/2012 1.4
8/24/2016 4.9
09/28/2016 5.4
11/02/2016 5.3
12/04/2016 5.3

05/26/2017 5.8 Switched from running to rowing March 2017
11/26/2019 10
01/02/2020 10
12/14/2020 9.8
01/10/2022 13.1
06/14/2022 14
01/13/2023 8.5
08/10/2023 14
05/06/2024 15.5
10/21/2024 11.7
01/07/2025 9.8
06/02/2025 12.3
07/09/2025 16.9
02/26/2026 7.5

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Replies to "Just looked at my post and realized the formatting of my PSA history got messed up...."

@tommm
Do you know how big your prostate is? A large prostate along with BPH could cause the high PSA issues you’ve been having. I know somebody who had a huge prostate, his PSA was always around 50 but a biopsy never found anything. Have you had any BPH problems? Have they ever put you on an antibiotic for your prostate? Those can affect your PSA.

A PIRADS 2 Barely Calls for a biopsy.

Good to hear you’re having another MRI before the next one.

Sometimes the cancer is in a spot that is not detected by the MRI. You can get a PSE test to see if you have cancer in your bloodstream and then a biopsy makes more sense. The PSE test is 94% accurate. If it finds something then they should do a much more thorough biopsy, more cores, To see if there’s something anywhere in your prostate.

@tommm
I’m not sure if there is a lot of diagnostic value from a 5th biopsy. The MRI I understand. I would be looking for an explanation of possible reasons why your PSA dropped so significantly in the last 8 months. That’s rather perplexing.
Am I reading it right that in 4 biopsies, the only cancerous area that was identified was a less than 1 mm 3+3? Just my opinion but the change to rowing and subsequent PSA bump (and continuing to be elevated) is suspicious.
Anyway, all the best/with any and all future testing.