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Is it PMR (and/) or Osteoarthritis?

Polymyalgia Rheumatica (PMR) | Last Active: 2 days ago | Replies (64)

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Profile picture for rayabw @rayabw

@dadcue You and I share a similar story. Developed PMR 11 years ago and was never able to go off prednisone until starting Kevzara about 1 1/2 years ago. But after starting Kevzara I developed osteoarthritis. Is it a side effect of the Kevzara or independent osteoarthritis? X-rays show moderate arthritis but the pain is more than moderate. Meloxicam helps but I’m a bit afraid of it

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Replies to "@dadcue You and I share a similar story. Developed PMR 11 years ago and was never..."

@rayabw
Prednisone is indiscriminate and reduces all inflammation, including osteoarthritis that will return at low dose or elimination of prednisone. I'm feeling it during my prednisone tapering because the pain that I had gotten used to gradually over time has returned all at once. Prednisone doesn't cure anything. It only takes away the inflammatory pain.

@rayabw

Osteoarthritis isn't a side effect of Kevzara. Most people our age have at least some "degenerative arthritis" which is caused by the "wear and tear on our joints" that happens over the years as we get older.

There is another kind of arthritis which collectively is called "inflammatory arthritis." People with rheumatoid arthritis (RA) have one kind of inflammatory arthritis which people know about. People who have RA tend to have severe damage to their joints.

PMR is an inflammatory condition that involves inflammation in the soft tissues surrounding the bone joints. It doesn't usually involve the actual bone joints themselves. It is said that PMR doesn't cause any bone joint damage but I believe it exacerbates osteoarthritis, makes it worse and causes it to hurt more.

As artificial intelligence says:

"Polymyalgia rheumatica (PMR) does not cause joint damage, but widespread systemic inflammation can amplify overall pain perception and make pre-existing osteoarthritis feel significantly more severe and painful."