I had terrible cognitive issues while on anastrazole. When my doctor switched me to Exemestane 8 months ago, I noticed a huge improvement and very minimal other side effects. I hope it goes well for you. I think more women should be informed of how severely hormone-blocking medications can impact their cognitive function, especially if they're still in the workforce. I found out I had cancer on my FIRST day of work on a new job almost three years ago, and started on Anastrazole the very next month. I was put in a trial to see if the AI would help shrink my tumor. It did, but the negative cognitive effects really hurt me professionally, as my supervisor (after I'd been on the Anastrazole for a year) started wondering what the heck was wrong with me as I began having serious issues with my working memory, focus, etc. It negatively impacted my job performance for my first two years until I finally started looking into it further. I just met with my department manager and she even commented on how much better I am doing in my roll, and how "everything seems like it's finally all come together for you" work-wise. That was really bittersweet to hear, because it shouldn't have taken me 2 1/2 years to learn my job, but the positive is that even SHE noticed the difference (my supervisor retired before I switched medications). Good luck!