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Muscle recovery time post 12 months ADT

Prostate Cancer | Last Active: 2 days ago | Replies (47)

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Profile picture for Jeff Marchi @jeffmarc

About half the people have their testosteronereturn to >280 3 months after they stop Orgovyx.

That allows you to rebuild your muscles. Low testosterone makes it extremely difficult to build muscles at the best. You can keep them where they’re at by heavily exercising.

In the HERO study, relugolix demonstrated sustained testosterone suppression superior to that of leuprolide acetate (97% vs 89%; difference 7.9% [95% confidence interval, 4.1–12%; p < 0.001]).

Men (N = 934) were randomized (2:1) to receive relugolix 120 mg orally daily or leuprolide acetate injections every 12 wk for 48 wk.

Overall, 74 of the 137 men in the relugolix cohort recovered to testosterone >280 ng/dl, with a median time to recovery of 86.0 d (95% CI, 65.0–92.0), versus two of the 47 men in the leuprolide cohort, with a median time to recovery of 112.0 d
https://www.sciencedirect.com/science/article/pii/S2588931123002900

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Replies to "About half the people have their testosteronereturn to >280 3 months after they stop Orgovyx. That..."

@jeffmarc hey Jeff, I think you ment in your first paragraph that the testosterone level returns to>280, NOT the PSA.