Welcome to Connect @donnieg, and @pamelaann1,

We're sincerely glad that you've joined us; thank you so much for posting your questions in this group. This is what Mayo Clinic Connect is all about: meeting others with similar experiences, sharing your journey, and learning from and supporting each other.

Here are a few discussions that you may wish to view:
– Clogged arteries at 86 yrs. old https://connect.mayoclinic.org/discussion/clogged-arteries-at-86-yrs-old/
– Aortic Stenosis & Valve Replacement:: https://connect.mayoclinic.org/discussion/aortic-valve-calcification/– What are the best methods for removing plaque from the artery? https://connect.mayoclinic.org/discussion/what-are-the-best-methods-for-removing-plaque-from-the-artery-what/
– husband's open heart surgery https://connect.mayoclinic.org/discussion/husbands-open-heart-surgery/

There are quite a number of Connect members who can share their experiences with you. I’m tagging @thankful @scottb @cynaburst @contender1 @HeartPatches @ronbee @llecrup @lyndamm @swanny @callalily74 @michael123 @yarrum @elvandi g @jackj @uncbball @contender1 @jc2buds to please join this conversation. I hope you can give @donnieg some insight.

We look forward to getting to know each of you better. @donnieg, may I ask what medications you are taking? @pamelaann1, would you share a bit more about the gene mutation you mentioned?