I was too intimidated by Tymlos or Forteo to start with those. The thought of injecting myself bothered me at the time. I went on Evenity for 4 months but had severe allergic site reactions and my dermatologist was concerned I could have a systemic reaction. Then tried Evista but got severe GERD and had to get an EGD. Then overcame my fear and went on Tymlos. Didn't really bother me at all except for lower back pain that started 10 minutes post injection and lasted for 30 minutes. I have to say I really liked Tymlos. But unfortunately my Medicare Part D doesn't cover it (I used samples from my rheumatologist). Would only cover generic Forteo at almost $500 per month. I realize there is a Medicare cap and also payment plans. Met with rheumatologist again and decided to give Evenity another try to speed up the process of bone building. He changed my protocol from zyrtec to benedryl and other than really bad site pain day of, and minor flu like symptoms 2 days later, which I had previously, I was fine. Fingers crossed. I like the idea of once per month injections covered by Medicare Part B knowing that I'll be a bit miserable for 3 days. But I did like Tymlos and it doesn't need to go in fridge. Hope that is of some help.