@tkw1 what did you do next?

@tkw1 - were your blood serum or saliva levels monitored when you were on HRT to see if you were absorbing an adequate amount to impact the bones?

@tkw1 What estradiol dose and, as @singingbones asks, was your resulting blood serum estradiol level tested? Thanks tkw1y. Sorry to hear about your outcome, and your experience is very useful information.

Here are some excerpts from the below linked article to show why this is important:
"Limited data suggest that up to 20% of women are “poor absorbers” of transdermal estradiol. It is essential that ‘poor absorbers’ with subtherapeutic levels are prescribed higher doses ..."

"... there is substantial interindividual and intraindividual variation in estradiol pharmacokinetics, resulting in up to 10-fold differences in estradiol levels between women using the same dose patch or gel. ..."

Title: The range and variation in serum estradiol concentration in perimenopausal and postmenopausal women treated with transdermal estradiol in a real-world setting: a cross-sectional study
https://journals.lww.com/menopausejournal/fulltext/10.1097/gme.0000000000002459~the-range-and-variation-in-serum-estradiol-concentration-in
Dr. Doug Lucas also explains why dose, and testing for response, matters in this video.