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Is PSA 0.032 after radical prostatectomy a normal fluctuation?
Prostate Cancer | Last Active: Jul 23 2:52pm | Replies (34)Comment receiving replies
I had very similar results after my robotic prostatectomy although I did not have a large prostate or a TURP beforehand. Also, I was 64 and not 53 when I started this journey. My Gleason score was 3+4=7. After surgery all was well. My PSA’s were undetectable for 4.5 years. The lab I initially used used to give values until it got to over 0.04. Then that lab was bought out and the new lab just reported “<0.1 wth verbiage that stated based on the AUA below 0.1 is undetectable. So after 4.5 years after surgery my last psa came back as 0.1!! I insisted on an Ultrasensitjve psa and that came back as 0.128. I will be starting Early Salvage Radiation on the middle of August. Don’t worry until it gets to .1 (hopefully it won’t) Becallo be your own advocate too. Good luck.
Replies to "I had very similar results after my robotic prostatectomy although I did not have a large..."
@jamie1957 Our stories are not all that different. RARP when I was 62 (2015). Gleason 3+4. I was undetectable (<0.1) for ten years. Then in June 2025 my PSA hit 0.11. I also had a nodule in my prostate bed that lit up like Christmas tree on a PSMA PET scan, but no mets beyond that were detected. I did 38 sessions of salvage IMRT (both prostate bed and pelvic lymph nodes) last fall (Sept-Nov). I did an usPSA test just before starting therapy that yielded 0.097. The IMRT went pretty well with only a few hiccups, and I haven’t had any lingering serious side effects, so far. PSA really hasn’t dropped yet. As I stated in a previous comment, I’ve had four usPSA tests since RT and they average to 0.097, with min of 0.086 and max of 0.113. Not what I expected, but I’ve since learned that it can take 2-5 years for your PSA to bottom after RT. My RO and urologist are not oncerned at this point, so I will just continue with quaterly PSA test and see where it goes. My optimistic interpretation is that the cancer is indolent (ten years before recurrence supports that), and if so the cancer cells are not dying from radiation damage because they are not dividing much. Whether my interpretation is right or not, I took the path of early intervention, like you, aiming for a better outcome than if I waited to hit 0.2.
Anyway, best wishes to you going forward with your salvage RT. “Full bladder and empty rectum” will be your daily mantra for a while.
Mel
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@jamie1957
Not sure what Becallo is but meant to type Be your own Advocate!?