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Nervous about switching from Letrazole to Exemestane

Breast Cancer | Last Active: Jul 5, 2025 | Replies (88)

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Profile picture for roberta75 @roberta75

Hi, I had my first estrogen positive progesterone positive cancer in 2017. I had a single mastectomy on my left breast with reconstruction Oct. 2017. I started Letrozole in Dec. 2017. I stopped the Letrozole in April 2023. I was diagnosed with triple negative breast cancer in my right breast May of 2025. I had a mastectomy on my right breast with reconstruction June 2025. No nodes in neither of my cancers were positive. I had 4 rounds of chemo from the end of July 2025 to the end of September 2025. So far I am doing fine. My hair has been growing back. I did continue exercising , walking and lifting weights through out these years. I have a wonderful trainer who has worked with me virtually. Thanks for your thoughts. It has been quite a journey. But, I feel very fortunate to have a caring medical team and I caught the cancers early.

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Replies to "Hi, I had my first estrogen positive progesterone positive cancer in 2017. I had a single..."

@roberta75 Hi, Thank you for your quick response. It was a surprise to me that Letrozole only protected you for 2 years and you had suffered the side effects for 5 years. I am leaning on letrozole to protect me. But the side effects was very unpleasant. So I was asking my Oncologist if she can agree with me to take once every other day since Letrozole has 48 hours half life. It is not a legal practice but the evidence approved. She said No. Some doctors allow patients to do it basic on a small group research she said. Now I am worried because my was E+P+ Her2 _ No node involved. Onco 22 and diagnosed at age 68 in 2024. I had left mastectomy too without reconstruction. I guess you are much younger than me. I have requested to have bilateral mastectomy at beginning but was denied. Now every year I have to do mammogram that worried me very much. Anyway, I have to face what is coming. You are so brave. I thank you so much for sharing your experience.Please keep in touch and take care!