@danboldman sorry no can help.
Did you check the Kevzara website for side effects etc?
Ask your dr.?

@danboldman
You’re not the first. I’ve read that can happen. My first time was in January 2026, so I took it late in the day. One hour before bed. I was fine during that hour and had no problem falling to sleep. I figured if it made me tired, it would be best to take at bedtime. Worst case scenario, I’d die in my sleep.
(Sort of just kidding)
The next day I felt fine.
I still take it in the evening, 12 injections later, just in case. I am tapering off, so the last 2 injections were 3 weeks apart instead of the normal 2 weeks.
I’ve had days like that but not Kevzara related and I always reflect back on the past few prior to it. I ask myself if I’m certain that you had done nothing differently the day before? Physically, foods, supplements, snacks, bed time?
Have you been around a lot of people, germs?
Good luck with it. Wish good health to you. Let us know if you rebound.

@danboldman
I know what the Kevzara directions say, but I prepare it differently.

It says to take it out of the refrigerator, keep it in the box to avoid light, and warm up to room temperature for at least one hour prior to injecting; adding not to heat it up by any other method.

Instead, I take it out of the refrigerator in the morning, right after I take my Prednisone, and leave it in the box under a towel to slowly warm it and keep it in the dark. In the evening, after supper, I take it out of the box and put it under my arm out for 30 minutes to an
hour (watch TV or occupy the time on my phone) because I want it closer to my body’s internal temperature.

People, I’ve read on this website, have mentioned that they injected it when it was too cold and that it was painful.

So, I am actually heating it up warmer than room temperature. Not in the microwave, submerging it in hot water, or anything stupid like that. I just simply place it under my arm and let my body slowly warm it up, closer to the temperature of my skin.
The liquid enters my body at approximately 90*-92*F, instead of 72*F.
I never feel it go in and I do know about injections. I get knee injections, every six months, and gave my mother daily insulin injections.

I never feel the liquid as it enters. I never bleed or see anything other than the circle imprint around the needle site from the device for a few seconds. It quickly fades to and I go on about my evening before bedtime.

Maybe this warmer method may help. Probably not, but worth a try. I’ve done it this way from the first injection.

I always feel better the next 48 hours after the injection, but it’s probably as much psychological as physical.

I wish you the best. If I didn’t explain my method well, let me know and I’ll make another attempt.