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Nervous about switching from Letrazole to Exemestane

Breast Cancer | Last Active: Jul 5, 2025 | Replies (88)

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I took Letrozole for over 5 years for ER and PR +. I also took Zyrtec to help with the pain. In 2025 I was diagnosed with TNBC . I had a mastectomy followed by chemo. It was suggested that I take Claritin for bone pain. It seemed to help. It might also help with AI side effects. Maybe check with your medical team to see if Claritin would help with side effects.

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Replies to "I took Letrozole for over 5 years for ER and PR +. I also took Zyrtec..."

@roberta75 Thank you for sharing. I have not heard about taking Claritin or Zyrtec to help with the side effects. I will ask my oncology team. Appreciate that information. Take good care

@roberta75
So sorry about your mastectomy! after the Letrozole?? did I read that right? I am shocked by that if I did. I am currently on Exemestane, and little to no side effects but I drink PROPEL a water supplement with electrolytes. It's been very helpful. What is TN, and the last two initials are breast cancer I think, right?

@roberta75 Hi, I have a question for you. You said that you took Letrozole for over 5 years. When did you stop taking letrozole and how many years after you stopped were you diagnosed with a new Triple Negative BC ? I found out that among the 3 AIs, Letrozole is most potent drug that reduces the Estrogen up to 96%. I read it could prevent a recurrence for up to ten years. Is that not the case? Hope you are doing better every day.