Hi @ferre, welcome to Mayo Clinic Connect. I’m sorry you’re dealing with this. Feeling constantly cold or having chills severe enough to keep you from going out sounds very disruptive. Since you’ve been taking Repatha for over a year before these symptoms started, I’d encourage you to let your healthcare provider know as soon as possible. They can help determine whether this could be related to the medication or whether something else, such as an infection, thyroid issue, anemia, or another medical condition, might be contributing.
While you’re waiting to hear from your provider, I’m wondering if you could share a little more. Did the chills begin suddenly or gradually? Do they happen all the time or mainly after your injections? Have you noticed a fever, weight changes, fatigue, or any other new symptoms?
I see @gently has similar concerns. I’d also be interested to hear if any other members taking Repatha have experienced something similar.
@jlharsh "AAll the tests have been taken, and even more, but everything is okay. I am perhaps 100% sure that Repatha is a major factor because it started exactly after I began using it. Generally, no medicines are good for humans, especially biological medicines, and they can have unpredictable, even very severe side effects. I understand that fear makes people take anything, but it would be good if these medicines were put under stricter control and research. Right now, people are being treated like guinea pigs. Repatha and all biological medicines are not meant for humans, no matter what is claimed. I believe the biggest culprit is Repatha – I have been to the doctor, but they only stare at the lab results without listening to how the patient actually feels. To be completely blunt, it’s starting to feel like I’ve already skipped one dose, and I will continue not taking it. It doesn’t matter what happens now because no one can endure this heavy freezing that completely paralyzes you. Who knows if Repatha has left a permanent mark on the body's temperature regulation system. Frankly, I am so angry that these expensive medicines are not studied in the long term, and that they think using Chinese hamster ovary cells (CHO cells) is acceptable. A human is a human, and that medicine does not correspond to the right way – using humans as guinea pigs. The text is harsh, but the symptoms are also terrible. I have stopped the medication because the coldness is so intense. We shall see. Thank you. I have taken the thyroid test and CBC (complete blood count), and now all the tests again, including T4 and B-vitamins, to see if that explains anything. Thank you.