@rpw2402 I had been on Trelegy for more than a year and it just seems like it was not working. Changed to Breztri and had better results. By inhaling deeply, the Breztri seems like it is getting deeper into my lower lung. There’s a LOT of discussion here on the Breztri inhalers not functioning properly. I’ve had no issues with that. Like the old saying: if all else fails, read the directions!