As a person who is on a second bout of PMR in 10 years, I have found Kevzara to be a game changer this time around. Have been able to steadily reduce prednisone since I have been transitioning to Kevzara and expect to be clear of it within a month or so. Down to 1.5mg now without issue. No significant pain.

Kevzara is not without its drawbacks. WBC and ANC is moderately low. The transition period with both Kevzara and prednisone further diminishes about to fight off bacterial infections. Having said that, have been around others with COVID and severe flu in past few months but have remained healthy.

Not all good, however, and infection concern is real. Right now battling a skin staff infection -- a case of poison ivy gone bad. It's not fun, but was aware enough to get into the doc and am having to go through a five-day regimen of antibiotics. But they are working, my skin is clearing up, and I'm feeling fine overall.

No easy answers here, but Kevzara has been an overall winner for me. Was in pain most of my first PMR bout. Feeling pretty darn good so far this time with right meds.