I started Anastrazole October 2025, & noticed my Rheumatoid arthritis pain really amped up by February. My oncologist strongly recommended an antidepressant that also addresses arthritis pain - Duloxetine. I finally went ahead with the drug in late May, & this week started getting mouth & throat sores. The literature states: "Get medical help right away" which makes sense as my throat was starting to swell up. I messaged both my GP & oncol, both of whom minimized the situation. I stopped taking duloxetine yesterday & already my throat has calmed down.
On a side note, I was taking the vaginal insert Estradiol for my prolapse, but my oncologist insisted I stop. Both my gyno & GP's nurse practitioner said it would be fine, so I've been researching & even the NIH says it's ok for those of us with estrogen positive recurring breast cancer. I'm prioritizing quality of life & going back on.