My psychiatrist isnt in a hurry to get me off of it. Instead she has me on three other drugs Buspirone, Seroquel and Ativan as needed. My regular doctor feels the mirtazapine should be tapered down. Iam trying to not get hooked on Ativan so iam careful how i take it.. If the drugs are working after all this time i shouldnt even need Ativan so iam wondering if the drugs are doing anything for me other than making me feel groggy and nauseated and depressed. I see my psychiatrist tomorrow and will ask her this. I have been on seroquel for 10 1/2 weeks, 5 weeks on Buspirone and 9 years on the Remeron (mirtazapine.