@zzotte wrote "I'm hoping that sooner than later they hit the jackpot"

The weird thing about hitting the jackpot treating a serious illness is that you might not even realise it at the time. For example, there was no big, magic "Aha!" moment for HIV/AIDS; they just kept tweaking the cocktail of drugs until they noticed that people were living 10, 20, 30+ years. Of course, they didn't know for sure until years later that they had got that right.

I have strong feeling that we're close that same point now with metastatic prostate cancer. Patients are living longer than the lagging SEER data would predict, not because there's a single brilliant cure, but because oncologists have figured out better ways to treat us with what they have (and added a few incrementally-improved drugs into the mix, like the 2nd gen ARSIs). But we won't actually know for many years, when they observe that many of us are (or aren't) still alive.