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What are your experiences with Leqvio?

Heart & Blood Health | Last Active: Jul 28 11:32pm | Replies (38)

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Profile picture for rnr1948 @rnr1948

I'm a 77 year old woman. My Dr. Has been concerned about my high cholesterol levels for years. My first shot was in February 2026 and the second shot in May 2026. The Dr. started me on Leqvio because of leg pain with statins. Since beginning the treatment I have had leg, foot, joint and muscle pain. The pain is increasing and hindering my ability to walk. I constantly afraid that I will fall. I have decided not to continue with the treatments and hopefully my leg weakness and pain will disappear.

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Replies to "I'm a 77 year old woman. My Dr. Has been concerned about my high cholesterol levels..."

@rnr1948 I'm sorry to hear this. I, too, have an aversion and intolerance to statins (specifically rosuvastatin which caused irreversible neuropathy in my feet) and chose to try inclisiran/Leqvio. My 3rd injection will be tomorrow. Would you mind telling me -- was the pain you experienced immediate? I ask because I am suddenly having pain in one ankle, making me more unsteady than the neuropathy symptoms. It feels like I twisted my ankle, but I haven't. It's 6 months past after the 2nd injection, so I'm thinking it's unlikely related to Leqvio. But it would be helpful to know more about your experience.
Thanks In advance.

@rnr1948 - Providing the rest of the story. My foot/ankle pain turned out to be tendonitis. It's better now but took a couple of weeks to turn the corner.