@leslie2121 Be sure to talk to your doc thoroughly about your plan to go from Tymlos to Reclast and back to Tymlos. My limited understanding of this is that Reclast will actually stay in your system for an extended time, even up to 10 years. If that is the case, your second round of Tymlos may likely be very suppressed, due to the anti-resorptive interference from Reclast. That is why the order of the drugs is so critical. Please do your homework with this in order to protect yourself. Best wishes!