@amishboy51 Yes a biopsy is done on the prostate "chips" that are the removed during HoLEP. It is one of the pros of this procedure. The large pieces of the prostate adenoma are pushed into the bladder then removed with a morcellator. These pieces are sent out for biopsy. The outer shell of the prostate is not removed so no biopsy is done in that area and unfortunately this area is where most prostate cancers are found so you can't say that cancer is ruled out. I don't believe that a biopsy is possible with Aquablation or some other BPH treatments. Thankfully my biopsy was negative. Thank you for asking.