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What if this prevents cancer from becoming resistant?

Prostate Cancer | Last Active: 41 minutes ago | Replies (50)
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So, many won't like what I'm writing, but it seems to be true.

I went to my doctor yesterday, and he said roughly the same thing dear @northoftheborder said, and I must say, it's terrible for a certain category of patients.

If you had stage 4 cancer with a large lesion/high Gleason score and high PSA levels (plus multiple metastases in lymph nodes, bones, etc.), then stopping ADT (remaining on lutamide alone) is tantamount to suicide. Hormone-dependent cancer (as soon as testosterone rises) will immediately begin to progress rapidly. In other words, you can't "tear the door" off ADT—you have to keep it closed constantly.

But for those with a small lesion, low Gleason score, and no metastases, stopping ADT is an uncertain option.

Good luck to all of us! I was very upset yesterday and stared blank for hours. There's almost no hope of avoiding resistance.

I shake everyone's hands in this thread. We fight while we can, guys!

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Replies to "So, many won't like what I'm writing, but it seems to be true. I went to..."
heavyphil | @heavyphil | 4 hours ago

@denis76 I think your doc is correct, but becoming castrate resistant is not inevitable.
Search the forum for ‘estradiol’, or ‘’Dr Weisserug’.
Jeff Marchi posted a conversation he had with the good doctor about this very topic…it’s very revealing ( all about suppressing rogue clones) and hopefully, encouraging. Best,
Phil

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Jeff Marchi | @jeffmarc | 41 minutes ago

@denis76
Sorry to hear you are in the same boat I am with probably lifetime ADT. I know I would really like to stop it, but it could shorten my life and it’s not worth it. Yes, there are a lot of side effects but the fatigue problem has never hit me so I can live with this. I know many people have a lot of fatigue from ADT, for them staying on it just does not work. I know a few people in that situation that are on Nubeqa alone, but most are in their late 70’s or 80’s and qualify of life is more important.

At least those with low-level cases of prostate cancer can usually stop ADT and live normal lives.

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