@mjm8491 I was the poster child for side effects: weight gain (mostly belly fat), hot flashes, ED, loss of libido, killer fatigue, diarrhea, loss of body hair, rise in Triglycerides and blood sugar, drop in red cells...every side effect on the Orgovyx.com website and more. Exercising about 75 minutes weekdays has helped some with fatigue, and I have to correct my eating in order to get the rest of my numbers back in order. Orgovyx did a great job on my cancer, taking the med for 18 months and having PSA <.01 and Testosterone <10 for more than a year. I'm three weeks post treatment and hoping for some recovery by Fall.