← Return to Have MCI, sharing new intel re Lithium Orotate

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@plus "... we've backed off to 5.8mg - 1mg Pure... brand + 4.8mg of the other. After a day or two of the 21mg combo my wife seemed a bit worse ..."

Followup: The 5.8mg didn't help, and in fact she kept getting worse. Now suspicious of the 4.8mg brand, I switched her to the 1mg "Pure..." brand and 5mg KAL 2xDay. Immediate slight and now continuing improvement. Hoping even more that our upcoming new neurologist with more Alzheimer's experience will prescribe LiO, so we might actually know what's in it.

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Replies to "@plus "... we've backed off to 5.8mg - 1mg Pure... brand + 4.8mg of the other...."

@plus I realize we are all wandering through the desert of resources hoping to find a productive path. But now that you and your LO seem to be in a positive place, I strongly encourage you to hold steady on dosage.

I cannot imagine that (a) there is a prescription that could be written for LiO. As far as I am aware the OTC mineral supplement Form is all there is. My guess is that best case you may get a ”let me know how that works out” from your Doc- and More likely you will get “let’s Wait For human trials” - which are seeking philanthropic funding since no pharmaceutical entity can monetize it - so-big pharma is out. Plus they are already in the game with the two approved drugs in trial now.

I encourage you to dive into understanding how LiO affects available lithium getting to the brain by avoiding sequestration within the amyloid plaques. And then how the trash amyloid plaque and tau must be removed - flushed out - and that Glymphatic process only occurs during slow wave non-REM sleep.

So there are a lot of moving parts in this process. LiO seems to facilitate some but not all of them. So i personally am working daily to achieve 12-15% slow wave sleep (SWS) that is not REM by using an apple watch and an app that is pretty consistent in how it classifies sleep stages.

My point is rather than trying to find the optimal dosage early, find one that isn't problematic - recognizing that less is more - and work on the other requisites to rid the brain of amyloid and tau proteins. It is all necessary to produce results.