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How long can you be on Xtandi?
Prostate Cancer | Last Active: 5 days ago | Replies (19)Comment receiving replies
@northoftheborder
During the intro from PCF, they specifically said that Darolutamide doesn’t pass the blood brain barrier. The test results they had, already showed that Darolutamide caused fewer brain issues. Sort of interesting they mentioned getting lost in a parking lot they were familiar with. I’ve never even faintly felt that problem. My wife has that problem and she’s not on any drugs.
Another interesting thing. Many people switched from Enzalutamide to Darolutamide, But no one switched the other way.
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@jeffmarc Yes, you're right. The clinicaltrials.gov page shows the trial as still in progress, but it appears that ARACOG has just presented its findings, and while patients on both Enzalutamide and Darolutamide showed a decline in cognitive test scores, the decline was greater on average with Enzalutamide. Also, the patients on Darolutamide eventually got better at the test with repetition (they remembered how it worked and gamed it a bit), while the patients on Enzalutamide did not.