@mnob yes, the oncologist said he tested and she's okay to metabolize. She just found a lump in armpit so she's getting a biopsy so meds on hold. She has metastisized kidney cancer that had gone to chest wall but it's indolent (very slow-growing). She's had breast cancer too. When she was in her 50s she did HRT and all the cancers she had are estrogen-driven. If it's kidney cancer, they may want to treat for both? We'll get second opinion to see what a big hospital suggests too. Just waiting now. Thanks for the replies everyone!