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How long can you be on Xtandi?

Prostate Cancer | Last Active: 5 days ago | Replies (19)

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Profile picture for northoftheborder @northoftheborder

@bluegill Yes, ditto for Erleada with me nearing the end of my 5th year.

Side effects like brain fog are rare with all the -lutamides, but they must be nasty when they happen.

There's never been an actual head-to-head trial to confirm which -lutamide is least likely to cause those cognitive side-effects (there are competing marketing claims for Erleada and Nubeqa based on the slim evidence of a restrospective human study and experiments on mice, respectively), but the majority won't experience them on any of the three.

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Replies to "@bluegill Yes, ditto for Erleada with me nearing the end of my 5th year. Side effects..."

@northoftheborder
At yesterday’s PCF online meeting about the ASCO Conference they discussed the difference between Darolutamide and Enzalutamide When it comes to brain fog. Darolutamide was much better and that also applies to apalutamide They specifically brought up the fact that Darolutamide doesn’t pass the blood brain barrier like the other two drugs. It’s a study called ARACOG. Here is a slide from that talk.