← Return to ADT, maybe not? Anyone opted out of ADT?

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ADT, maybe not? Anyone opted out of ADT?

Prostate Cancer | Last Active: 3 days ago | Replies (162)

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Profile picture for monahanirvingjames @monahanirvingjames

I have been taking Orgovyx now for 53 days. I finished day 10 of radiation for cancer in my iliac lymph node.I had my prostate removed in 2018 and was diagnosed with 4A metastatic cancer in March. I hate the orgovyx. I spoke to my oncologist and he suggested I could stop after my 33 days of radiation. Thoughts on the drug? Thoughts on stopping? I feel like it has ruined the quality of my life and I will never be the same. Thanks, Jim

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Replies to "I have been taking Orgovyx now for 53 days. I finished day 10 of radiation for..."

@monahanirvingjames
Whether you should stop Orgovyx Depends on the severity of your prostate cancer Diagnosis.

If you are Gleason nine or 10 and have aggressive issues found in your biopsy like the following. intraductal, ductal, large cribriform, Seminal vesicle invasion, EPE or ECE. (Extraprostatic extensions extra capsular extensions). They can make the cancer much more aggressive.

In that case, you would be much better off continuing Orgovyx For 18 months to two years.

If you are a Gleason 3+4 or 4+3 then a minimal amount of time on it might not make a difference.

Everyone is different. Did you get a decipher score and find out what your chance of reoccurrence is? The higher the chance of reoccurrence the more likely you need ADT for an extended period of time.

I was a Gleason 4+3 and I’ve been on it for eight years. I had surgery and then radiation and I’ve had four reoccurrences total, So far. I have a genetic problem BRCA2, which makes it much more aggressive. In my case, stopping it could be quite detrimental. I have been around 16 years with it so treatment has been beneficial.

Like I say, everyone is different.

@monahanirvingjames Ditto what Jeff posted…I will only add that I understand totally why you want to stop the Orgovyx.
But the ADT significantly weakens the cancer and it makes radiation that much more lethal.
Continuing after radiation has a great impact on those somewhat resistant cells ( we all have them) which did not suffer ENOUGH from the photons.
Depriving them of T is like withholding food from a dying man: if he’s not dead yet, he soon will be!
Ask your RO the absolute minimum duration of ADT he would advise; I think it’s 4 months but not really sure.
Phil