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Possible Prostate Cancer: Are there side effects of MRI fusion biopsy?
Prostate Cancer | Last Active: 5 days ago | Replies (69)Comment receiving replies
@brianjarvis I'm 69 & I've been getting tested once a year for years. My PSA jumped from 3 to 4 in November 2025 which is when my primary referred me to a urologist.
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@kpg7121 That’s good that you had been monitoring PSA for so many years. Most guys don’t do that.
What’s missed sometimes is that PSA just tells part of the story. In your case, it wasn’t just the PSA itself, it was the jump in PSA Doubling Time (or PSA Velocity) that raised concerns.
There’s also the % Free PSA that’s not usually monitored, but also gives more insight. (PSA circulates in the blood in two forms – either attached to certain blood proteins or unattached (“free”). If the % of Free PSA is low (<25%), it may indicate the need for further testing.)
Then, once you’ve had an MRI, the PSA Density tells more of the story. (PSA Density is the ratio of PSA to prostate volume. The larger the prostate volume (due to an enlarged prostate), the more PSA can be produced.)
With each diagnostic step you can build on earlier information to gain more confidence in decisions.
Good luck going forward.