@kpg7121 The biopsy report not mentioning cribriform, IDCP, ECE, PNI is all good. 1 out of 12 samples is good too. But 3+4 is cancer, even if it's one core sample. Sometimes the pathologist makes a mistake, I had one pathologist at Mayo say 3+4, but then at another COE said 3+3, then post-surgery at Mayo I was downgraded to 3+3. Sounds like you like your Urologist, hope that he/she is truly knowledgeable about options for treating prostate cancer. Options are usually Active Surveillance or treating with surgery or radiation. From what I know, Active Surveillance is often an option for 3+4. Some people will get a 2nd reading of the biopsy samples. Some people will have testing (Decipher test) done on the cancerous biopsy sample to see if it is likely to spread. Some people have genetic testing done on themselves to see if they have genetic mutations that make prostate (and other cancers) more risky. All things you can talk to your Urologist about. Many more knowledgeable people here than me, but wanted to share what little I know.