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Treatment of lung adenocarcinoma
Lung Cancer | Last Active: Jun 22 9:07pm | Replies (38)Comment receiving replies
@tongxiaozhi, that's certainly a scary reaction. Has she stabilized now, and is she feeling better?
Do her doctors believe it was the medication, or some other cause for these events? Some people do well on a lower than standard dose of the targeted therapy medications, but it's certainly best for her doctors to determine what's best. Are you and your family able to help her through this illness? It has to be a difficult time for all of you.
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@lls8000 Thanks for your reply and your kind words of comfort.
She is awake and feeling better now. The doctor believed that Osimertinib was not the main cause. My family are taking care my mom well. We will discontnued Osimertinib for a while and re-evaluate the possiblity of restarting it after two weeks.
We took osimertinib for two weeks and did a follow-up check. The blood routine and liver function were both normal, but the platelet count dropped from 150 to 100. After continuing the medication for another month, she caught a cold during that period. One day she suddenly vomited, and at night we sent her to the hospital. The doctor said it was an acute myocardial infarction.
Angiography showed a large thrombus in the coronary artery. The doctor said the main cause was still atherosclerosis. In addition, my mother had two previous mild strokes and has been taking antihypertensive medication continuously.
Now she is hospitalized for further tests, and her liver function is also abnormal. The doctor said it may be due to osimertinib; however, the doctor also said that the main cause of the myocardial infarction was not osimertinib, but that it may have had some contributing effect.
After the heart attack, her platelet count dropped to just over 50. It is unclear whether this is due to the myocardial infarction or the effect of osimertinib