@gowalking Originally, I had the dizziness, nausea, and headache immediately afterward each injection, starting with my first injection at full dose on March 20, 2026. I also had severe bone pain in my lower body (including feet and ankles at night), along with crazy-strong nerve sensations of something clawing/scratching up the front of my shins. Walking became more and more challenging, due to lower body bone pain. Increased lower body swelling, sweating (esp at gym and at night), significant fatigue (afternoon), and sleep disturbances didn't help to tolerate the other issues. The stomach distention was insane and still can be. Majority of the above are much improved with the lower dose. Sadly, my health provider has pushed back strongly on my reduced dose, as it is "not FDA-approved" and will not offer any recs re: dosing, etc. She was terribly reluctant to allow me to continue, due to no guidance from Radius. It took strong point and convincing to get her to allow me, RELUCTANTLY, to continue...with refills only being provided one month at a time, which is stressful. I cannot imagine what Reclast will do to me, when the time comes. She mentioned it woukd likely be a half-dose and I asked about the extra IV hydration, longer infusion time, and Tylenol.

After the first 24 injections, I started developing half-dollar-sized angry welts at the injection sites (took about 24 hrs to fully raise and about 5-8 days too subside. I'm still dealing with the welts, but they seem to be less angry the past week, with an occassional flare ot two. Can't really hide those from my provider. (As much as I tried to titrate back up to full dose by 10 mcg every 10 days, I was stopped in my tracks at 60 mcg...quickly dropped back to 50 mcg, and then to 40 mcg. I have been on half-dose now since May 16th.

My last P1NP:CTX ratio was good at 181 (anabolic is believed to be 150+). At that time, I had been on full-dose for about 3 of those 6 weeks. I retest again in early July. I sure hope my ratio manages to stay strong.