@suecedar1028 my health started going down hill after my 2021 second Covid shot. The left side of my face began flushing and has never stopped. My left salivary gland was swollen for four months. I felt like I had a fever off and on for those four months also, but when my temp was taken it showed no fever. Long story short, that's when my Mast Cell Activation Syndrome began I believe and every time I get the flu, or any virus my health gets permanently worse. But I've just discovered all these symptoms I have (flushing, itching that begins and ends spontaneously, bloating, edema, fatigue, brain fog) are those of Mast Cell Activation Syndrome. I started the first line treatment of zyrtec and pepcid taken together twice a day. After a few weeks my face flush was fading, gut bloating significantly better so I've read if symptoms improve from this it is likely Mast Cell Activation Syndrome. Unfortunately, to get those results I had to take meds twice a day and I started having serious short term memory issues so I had to stop. Memory issues are improving since stopping about a week ago. Now I'm on the hunt for someone to prescribe cromolyn sodium, the next most common treatment for MCAS. I was very active prior to that 2nd covid shot, but was required to take it because I work in a healthcare company. Kim