@loriesco
I understand how you feel. I don't really know how long I had gout and it doesn't really matter to me. I only regret that I took so much Prednisone for a very long time. Prednisone daily probably prevented me from knowing if I was having gout flares.
I'm on allopurinol and colchicine now. My uric acid level is targeted to be under 5 mg/dl. I'm also on potassium citrate to shrink the size of my uric acid kidney stones.
"Reduction of Urine Acid. Uric acid stones form in acidic urine, so a key goal is to make urine more alkaline (or basic, with a higher pH). This is often done with medications called potassium citrate or sodium bicarbonate."
https://www.kidney.org/kidney-topics/uric-acid-kidney-stones
There seems to be a lot that could have been done. I didn't need all the pain I went through when I passed that kidney stone!
-------------------------
For gout patients with tophi (urate crystal deposits), doctors typically lower the target serum uric acid level to < 5 mg/dL. Standard treatment normally aims for < 6 mg/dL.
Nobody really knows how high my uric acid levels were getting because it was never checked. When I passed the uric acid kidney stone, my uric acid level was > 8 mg/dl. I might have been able to change my diet and do other things to keep it lower had I known.
What I found interesting is that IL-6 inhibitors like Actemra which I currently take for PMR might also help with the management of gout.
https://www.healio.com/news/rheumatology/20240219/biologics-fill-very-unique-niches-in-gout-management
The quote below is from the above link:
"Shifting gears, IL-6 inhibition with tocilizumab (Actemra, Genentech) may also have utility in the acute gout flare setting, according to Mandell."
---------------
The following link provides more details if you are interested:
https://www.mdedge.com/internalmedicine/article/272016/gout/il-6-receptor-inhibitors-show-early-promise-cppd
@dadcue I am always interested, but I was confused and I have this question for you. Do you have CPPD go or do you have uric acid type gout? The CPPD is the calcium deposit one that I was referring to the uric acid level one is when your body goes acidic. The treatments are different. I have the high uric acid level gout. The pseudo gout is the CPPD. I want to point out that the biologic are very harsh kind of like the prednisone so before you start getting excited about those remedies, I want to be sure that you’ve investigated, and they have told you which you have the pseudo, gout or the gout. If you have the gout, then pushing your body to be alkaline is what you need to do either from low purine diet, drinking liquids that push your body alkaline like a squeeze of lemon in your water daily and the allopurinol. The CPPD is a different protocol which it sounds like you’re on with the colcherine. I probably spelled that wrong.! maybe they think you have both. My father had gout and I never knew it because it was well controlled. My mom used to make him a thermos to take to work every day with warm water and a squeeze of lemon. My father never drank anything anywhere anytime any place other than hot water with lemon and I never knew he had gout until my mother died and he stopped getting the lemon in the water. I have pretty much given up alcohol because my body is not interested in it which is a good thing cause that’s not good for you either when you have pseudo, gout or gout. And like I said, I keep a low purine diet and sometimes I can start to feel a twinge in my big toe so I just start flushing water and alkaline type drinks and I’ve never had another gout flare since my initial ones 25 years ago. But achy and stiff like you wouldn’t believe until I started taking the tart cherry capsules, and then the allopurinol.