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One variable confounding all these studies is that osteopenia and osteoporosis have long been and are still being treated with drugs that reduce bone strength all the while increasing bone mineral density.
(Are fractures more common among those with osteopenia than those with osteoporosis because they are most commonly treated with bisphosphonates?)

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Replies to "One variable confounding all these studies is that osteopenia and osteoporosis have long been and are..."

@gently You might be interested in an article I posted yesterday under this heading: "Study: 2/3rd of All Fractures Are Not Attributable to Osteoporosis"

Also, there are articles that discuss that bisphosphonates offer little benefit as far as fracture prevention. I can provide a link to a couple if you are interested.