Connect
← Return to Salvage metastasis-directed therapy versus elective nodal radiotherapy
Discussion
Salvage metastasis-directed therapy versus elective nodal radiotherapy
Prostate Cancer | Last Active: 4 days ago | Replies (6)Comment receiving replies
@thmssllvn
PSA is just one of many parameters. Very aggressive PC actually often produces less PSA than indolent. We were told that by our urologist. My husband had cribriform, IDC and gleson 9 and his PSA was about 5.4 before surgery. I personally would not use PSA as the only parameter for making any decision regarding PC treatment.
Replies to "@thmssllvn PSA is just one of many parameters. Very aggressive PC actually often produces less PSA..."
Connect
@surftohealth88 Good comment, I would only add that BCR was the only benefit for 'prophylactic' (50% dose/strength) pelvic lymph node radiation....
in the absence of metastasis. My comments would not apply to the your husband's case after surgery. The study dealt with oligometastatic pelvic disease. This means 5 or less than 5...but 1 is 20% and 5 is five times, i.e., 100%. I do not have access to the full article to determine what the one pelvic lesion SBRT versus the general pelvic 'therapeutic' [?] radiation dose. From the summary available only the term oligo... is characterized which is equal to as little as one or as many as five lesions. 13% improvement for 3,4 or 5 may evaporate for 1 or 2 lesions or be within a margin of error. Another chapter in the Annals of Lumpers and Splitters. There is a big difference in prophylactic (50% dose) use in PSMA PET SCAN non metastatic disease and documented pelvic metastasis. The avoidance of inappropriate conflation in dissimilar clinical presentations was my intention. The dissection of the hyperlinked study is merely a gratuitous foray by an interested side liner.