@irenea8 I was diagnosed with CF five years ago, after a positive sweat test and a DNA study by Johns Hopkins. I have also had countless blood tests and sputum samples for a variety of other issues (heart disease, anemia, periodic lung infections, etc.), but nobody has ever suggested that any findings from those were indicative of CF. I do have Bronchiectasis, so my sputum samples are probably no different than those of anyone with non-CF Bronchiectasis. Hope that helps.