@hoping4cure I totally understand what you are going through.
I was diagnosed with vaginal melanoma in 2022 and went through immunotherapy for 14 months. I had surgery and my OBGyn Oncologist got good margins. I was cancer free for 18 months before I discovered a recurrence in March of 2026. I was getting Signatura tests every 3 months, but it did not detect the tumor. Apparently it had not shed into the blood, which is how Signatura detects the cancer. A PETscan showed the tumor has not spread and is in the same area as the last tumor. I have started immunotherapy again and am optimistic that it will work again this time. My Oncologist has stated that I will be on immunotherapy for a very long time. I also know some infusion nurses that told me there are people who have infusions once a month for years.
I know it is scary, but immunotherapy is very new and what it has accomplished so far is amazing. The internet is a very scary place and a lot of what is out there is old.
Have faith that you will get through this, and remember there are new ways to fight these cancers every single day. A few years ago we didn't have any sort of treatment for Melanoma.
I hope you are doing well and your cancer is in remission!