Thank you for letting me know that. I also take Doxycycline one time a day but it's due to my eyes getting Occular Rosacea and Psoriasis in them. I didn't even know that was possible until it happened. They are lowering me in how many times I take it due to it affecting kidneys if taken long term. I find it helps the Occular Rosacea and Occular Psoriatic issues though to make the effects feel some relief. Do you also have this issue? How long have you been doing it? I think mine has been about a year now. I still get bad redness and heat in the face but less breakouts.