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Upping prednisone dose during a flare

Polymyalgia Rheumatica (PMR) | Last Active: Jun 13 1:37pm | Replies (11)

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Profile picture for petermccarville @petermccarville

1. Make sure that you are actually dealing with a flare of PMR and not the adrenal insufficiency that , by many accounts, can mimic the PMR pains. They did for me but patience and sitting with "some" pain at those crucial taper points (below 5 mg) helped me. The so called flares mellowed and went away on their own. Everyone is different, however. I can successfully say that I did not have the classic PMR pain when tapering. All my pain was gone during the prednisone journey and my lab numbers stayed down during that journey. Pred was working, in other words. 2. Try the biologicals (actemra and Kevzara) if you are assured it is a stubborn point in your tapering. 3. taper VERY slowly once at 5 mg. I did .5 mg every 2-3 weeks below about 3-4 mg. The last few milligrams took almost as long as the first 10. 4. Try the tylenol extra strength to weather these possible adrenal insufficiency storms. 5. Hang in there. 6. keep asking questions about whether this a flare or not. I, fortunately, never had flares but did have weird pains at lower prednisone doses which I could have mistaken for flares. Also, length of time on prednisone, age, commorbidities, and severity of PMR originally all play a role in how well one tapers. 7. Remember, tapering to 0 prednisone is possible and to live without PMR is too. I have since March 2026 after a year journey with PMR and prednisone. Not as many of us who have gotten thru PMR write into this chat room but we do exist!

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Replies to "1. Make sure that you are actually dealing with a flare of PMR and not the..."

@petermccarville

I think people like you should be celebrated. Most people do overcome PMR in a year or two and successfully taper off prednisone. I'm more interested in those stories because maybe I can learn more about what works. I spent "decades" on prednisone so I'm well versed on what doesn't work.

It is similar to being magical to me that people are able to taper off prednisone relatively quickly. There was nothing very magical about increasing my prednisone dose for every pain that recurred over and over again. The goal should be to make PMR go away and to get off prednisone as soon as possible. I can't say the waiting for PMR to "burn itself out" ever got me anywhere. On the other hand, I eventually had to stop adjusting my prednisone upwards and I had to wait for my adrenals to recover.

I don't think "seroid sparing medications" should be shunned in favor of more prednisone. Thanks to a biologic, I was finally able to taper off prednisone. Otherwise, I would have never been able to taper off prednisone no matter how slow my taper was. The biologic I take controls PMR without the long-term toxicity of prednisone and enabled me to taper to zero after more than 12 years of prednisone. The nice thing about the biologic -- the biologic doesn't suppress my adrenal function like prednisone did. I had to overcome adrenal insufficiency in addition to PMR and some other things because isolated cases of PMR don't tend to exist very often.
https://rheumatoidarthritis.net/clinical/beyond-steroids-pmr