Hello @venki, It must really be frustrating to not be able to get answers and have your doctors not seeming to care about your condition. I see this is your first post in a few years so I would like to welcome you back to Connect and hopefully you will be able to find some answers. I think what might be helpful is to learn what members have shared in this older discussion which has newer entries.

- Cerebral Small Vessel Disease: https://connect.mayoclinic.org/discussion/i-have-vascular-small-vessel-disease-that-so-far-just-has-caused/?commentsorderby=DESC#chv4-comment-stream-header

Mayo Clinic has a list of treatments for small vessel disease that may be helpful
- Small vessel disease - Diagnosis & treatment: https://www.mayoclinic.org/diseases-conditions/small-vessel-disease/diagnosis-treatment/drc-20352123