@neciern Do you know the 'pattern' of your ANA results? I've had some of the same issues as you have had, but not as much. There is a pattern to the ANA test that will help with diagnosis. Mine was a homogenous pattern, which I believe is SLE (Systemic Lupus Erythematosus), but there are several other patterns that can be quite different. A specked pattern can indicate SJD (Sjogren's Syndrome)or connective tissue disorders as an example. In those examples, a rheumatologist might be able to help you and could work alongside your gastroenterologist. Sometimes we need a patient advocate to help us along and organize these complicated things.