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Gleason 6 Gland Boundary

Prostate Cancer | Last Active: Jun 10 2:58pm | Replies (7)

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@brianjarvis
Got my decipher score a while back, and genetic testing. Pursuing a second opinion on pathology now, but haven't achieved it yet. Probably should be contemplating a follow up biopsy. Anything I've missed?

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Replies to "@brianjarvis Got my decipher score a while back, and genetic testing. Pursuing a second opinion on..."

@rport3 There are a number of tests that can be checked while on active surveillance to give additional insight into the status of the disease:

> Standard PSA test. (But, preferably a PSE test. This Prostate Screening EpiSwitch test is significantly more accurate than the standard PSA test for detecting prostate cancer.)
> % Free PSA (While your PSA is between 4.0-10.0)
> PSA Doubling Time
> PSA Velocity
> PSA Density

Consider another biomarker test besides Decipher, one that will provide additional relevant information. There are many different tests depending on what you’re looking for:
> FoundationOne®Liquid CDx; Guardant360; Caris Assure.
> Prolaris; OncotypeDx.

Liquid biomarker tests:
> (blood): 4KScore; EpiSwitch PSE; Phi Prostate Health Index;
> (urine): SelectMDx; PCa3 (PC Antigen 3); MyProstateScore (MPS), ExoDx.

(I’ve probably missed others.)

What you want to do is to monitor to ensure you have a “true” Gleason 6. Those don’t metastasize. (https://youtu.be/NV8QHzbgamI)

With that amount of “active” surveillance, the status of the disease can be closely monitored - you’ll know if anything changes as soon as it changes.