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Has anyone had experience w Leflunomide( Arava)?

Polymyalgia Rheumatica (PMR) | Last Active: Sep 23 11:31am | Replies (8)
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Profile picture for anirose @anirose

I had PMR 2024. Was put on Prednisone 20mg. Weaned off slowly over two years! Had a couple of flares so my pred went up sometimes. My Rheumatologist added Lefludimide. I have been taking that since May 2025. Prednisone was finished end of Feb. Lately about 3 weeks, I have been getting extreme nausea and soft stools. I am having a liver panel and abdominal ultrasound today. Anyone else get those symptoms when just on Lefludimide ? I read it can cause nausea.

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Replies to "I had PMR 2024. Was put on Prednisone 20mg. Weaned off slowly over two years! Had..."
stubwolf11 | @stubwolf11 | Sep 23 11:31am

@anirose I have been taking 5 mg of prednisone for two years and still in pain when the dose wears off so my rheumatologist has suggested 10mg of lefludimide for 10 day trail with my prednisone.
I’m a little apprehensive because of the side effects. Do you find it helps with your pain?

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