Hi! @lkng67 :

I am so sorry for all you've been through, Lkng:( Journey of fighting the disease of cancer truly is a bumpy road, isn't it?

I am not any medical expert, but please get your pain evaluated before deciding it is truly from taking Anastrozole. Please allow me to use my own personal experience to explain why. As I stated before: I have been taking Anastrozole since 1/18/24, and have been utilizing a PT/OT rehab program for cancer patients to mitigate any aches & pain due to the lack of estrogen hormone production in my body. As it happens, I've been experiencing this unrelenting pain ever since 12/19 of last year myself. It started with a sudden deep bone pain in my left hip, saw the internal medicine physician on 12/23 and was given some prescription muscle relaxer; unfortunately it turned worse and started its downward spiral. Finally had an MRI done on 12/31/25 for the spine and hip, and it revealed that there's a 1.4 cm cyst pushes to the left side of my Lumbar spine at the Nerve Root Base that sends the radiating pain through my left hip towards the entire left leg, ankle and the toes thus causing the challenge in walking and all pain. I saw an orthopedic spinal surgeon on 1/29/26 and discussed several treatment options with him; I decided to take oral steroid medication (for 10 days) to calm the urgent inflammation first, and proceed with physical therapy sessions to strengthen my muscle to support the back, spine & all. I am so sorry for my lengthy note; but I am striving forward with whatever strength that I can gather. I am still going for PT sessions twice a week - without any pain medication - right now; even though the numbing pain still exists in my left lower leg and ankle, but with much less intensity and I can walk "normally" and proceed with daily functions as normal as I can, and went back to serve at soup kitchen voluntarily since March, and I am still taking Anastrozole to prevent any future recurrence or metastatic of cancer.

So please have your pain evaluated by a medical specialist to find out the essential cause of your pain. Perhaps ask for an MRI to find a more detailed assessment. You'll be in my thoughts and prayers, Lkng; for I consider you as one of my comrades.

Wishing you all a better journey ahead with hope, love, and peace!