@kjoed53 , I don’t have PMR. I follow this group because it’s the one I found the most information on from people who use prednisone long term. I have asthma and chronic sinusitis which required steroids and then unfortunately after each burst becoming more and more difficult to come off of, I develop secondary adrenal insufficiency. Now every time I get sick or have major stress from an injury, surgery etc. I have to stress dose which repeats the cycle of trying to start a new wean. I’m currently at 8 mg and this wean is going very slowly. I’ve never had depression or been emotionally labile prior to being on prednisone.