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Prostate Cancer | Last Active: Jun 10 1:51pm | Replies (101)
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@bikeman1
You have to take prednisone while on abiraterone (zytiga) . I always wondered why so I checked and abiraterone shuts down your adrenal glands. One more complication! The -amides, like darolutamide ( nubequa) don’t do that. And I think it might cause more heart issues - Mrs Surf can tell you more.
That said, several people on this forum have benefited from abiraterone - everyone responds differently.
Replies to "@bikeman1 You have to take prednisone while on abiraterone (zytiga) . I always wondered why so..."
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@klein505
To be more specific, abiraterone Stops the production of cortisol. Without it, you get extreme fatigue. Prednisone restores the cortisol that is lost. For some people 5 mg doesn’t work and they need 10 mg. After you stop abiraterone Your body does not usually produce cortisol immediately. It can take a month or two or three of tapering off before your Cortisol returns completely. I thought mine would return in one month, In the afternoon, I would have extreme fatigue and have to sleep for a while. One month wasn’t enough For me and for most people.